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Chronic administration of NSAIDselective cyclooxygenase-2 inhibitorsacetylsalicylic acid3 g/day and non-selective NSAIDsmay reduce the antihypertensive and diuretic effect of ACE inhibitors and thiazide diureticsNSAID and ACE inhibitors may exert an additive effect on the increase in serum potassium and may result in a deterioration of renal functionThese effects are usually reversibleRarelyacute renal failure may occurespecially in patients with compromised renal function such as the elderly or dehydrated.
If you need surgery or medical teststell the doctor ahead of time that you are taking medicine that contains hydrochlorothiazide.
High potassiumnauseatingly feelingchest painirregular heartbeatsloss of movement;
If you have diabetesthis product may affect your blood sugarCheck your blood sugar regularly as directed and share the results with your doctorYour doctor may need to adjust your diabetes medicationexercise programor diet.
ACE inhibitors cause a higher rate of angioedema in black patients than in non-black patients.
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you should not use zestoretic if you are allergic to hydrochlorothiazide or lisinopril, or if .